What should I check before giving cyclophosphamide?
Monitoring and Testing While Taking Cyclophosphamide Periodic blood work will be obtained to monitor your complete blood count (CBC) as well as the function of other organs (such as your kidneys and liver) will also be ordered by your doctor.
How do you take oral cyclophosphamide?
Usually it is best to take cyclophosphamide first thing in the morning, to reduce the risk of bladder problems. However, your doctor may want you to take it with food in smaller doses over the day, to lessen stomach upset or help the medicine work better.
What instructions should be given to a patient taking cyclophosphamide?
Take cyclophosphamide exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor. Swallow the tablets whole; do not split, chew, or crush them.
What should I monitor with cyclophosphamide?
Your doctor will order regular lab tests to check your response to cyclophosphamide and monitor for toxicity. Your blood counts – white blood cells, red blood cells and platelets – will be checked regularly. Your liver enzymes and urine will be checked regularly as well.
How toxic is cyclophosphamide?
Clinically, damage to the bladder (haemorrhagic cystitis), immunosuppression (when not desired) and alopecia are the most significant toxicities associated with cyclophosphamide. Cardiotoxicity is also a possibility when very high doses are given.
What organ is affected by cyclophosphamide?
Blood in the urine warning: When cyclophosphamide is broken down by your body, it creates substances that irritate your kidneys and bladder. These substances can cause your kidneys or bladder to bleed.
What is oral cyclophosphamide?
Descriptions. Cyclophosphamide is used to treat cancer of the ovaries, breast, blood and lymph system, and nerves (mainly in children). Cyclophosphamide is also used for retinoblastoma (a type of eye cancer mainly in children), multiple myeloma (cancer in the bone marrow), and mycosis fungoides (tumors on the skin).
Is cyclophosphamide given orally?
Cyclophosphamide can be given by intravenous (IV, into a vein) infusion or taken orally (by mouth) in a pill or capsule form. This information is about the oral (by mouth) formulation. Oral doses should be taken whole (not crushed, chewed, or broken) and with food in order to decrease nausea.
What is the action of cyclophosphamide?
Cyclophosphamide is used to treat various types of cancer. It is a chemotherapy drug that works by slowing or stopping cell growth. Cyclophosphamide also works by decreasing your immune system’s response to various diseases.
What is the toxicity unique to cyclophosphamide?
Clinically, damage to the bladder (haemorrhagic cystitis), immunosuppression (when not desired) and alopecia are the most significant toxicities associated with cyclophosphamide.
What is the antidote for cyclophosphamide?
No specific antidote for cyclophosphamide is known. Overdosage should be managed with supportive measures, including appropriate treatment for any concurrent infection, myelosuppression, or cardiac toxicity should it occur.