What medications should you avoid with Zoloft?

Sertraline should not be taken with or within two weeks of taking monoamine oxidase inhibitors (MAOIs). These include phenelzine (Nardil®), tranylcypromine (Parnate®), isocarboxazid (Marplan®), rasagiline (Azilect®), and selegiline (Emsam®).

What medications interact with sertraline?

Some products that may interact with this drug are: pimozide, other drugs that can cause bleeding/bruising (including antiplatelet drugs such as clopidogrel, NSAIDs such as ibuprofen/naproxen, “blood thinners” such as warfarin/dabigatran).

How do I wean myself off of Zoloft?

Gradually tapering off Zoloft under a doctor’s supervision can reduce or avoid the symptoms altogether. Usually, sertraline’s dose is gradually reduced over around four weeks. A sample taper schedule is reducing the dose by 50 mg every 5–7 days to a final dose of 25–50 mg before the drug is stopped.

Can Zoloft give you joint pain?

Physical Symptoms. When you first begin antidepressant treatment, depression medication side effects can be physical symptoms like headache, joint pain, muscle aches, nausea, skin rashes, or diarrhea. These symptoms are usually mild and temporary.

Can you take Zoloft with methadone?

Using methadone together with sertraline can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.

What happens if you miss 2 days of Zoloft?

If you forget to take your tablets for a few days, you may start getting your old symptoms back, or get withdrawal symptoms (feeling dizzy or shaky, sleep problems [including difficulty sleeping and intense dreams], feeling irritable or anxious, feeling or being sick, and headaches).

Can sertraline affect arthritis?

Results: The sertraline-treated rats showed a significant reduction in clinical arthritis compared to controls, at all doses given, accompanied by a significant increase in interleukin 10 and a decrease in tumor necrosis factor-α levels and cycloxygenase-2 production, without lymphotoxicity.

When is the best time to take Zoloft 50 mg?

Typically, your doctor will recommend that you take your prescribed dose of sertraline once a day, either in the morning or evening. If sertraline makes you drowsy, your doctor may suggest that you take it at bedtime.