What is benzoylecgonine?
Benzoylecgonine is the main metabolite of cocaine, formed by the liver and excreted in the urine. It is the compound tested for in most cocaine urine drug screens.
What is the date s for benzoylecgonine?
Date s. Modify. 2021-03-27. Create. 2005-06-08. Benzoylecgonine is the major metabolite of cocaine. It is formed by hydrolysis of cocaine in the liver, catalysed by carboxylesterases. It is excreted in the urine of cocaine users after processing in the liver. It is the main pharmaceutical ingredient in the investigational drug Esterom,
What is benzoylecgonine in a urine drug test?
Benzoylecgonine is the compound tested for in most substantive cocaine urinalyses. It is the corresponding carboxylic acid of cocaine, its methyl ester. It is formed in the liver by the metabolism of cocaine, catalysed by carboxylesterases, and subsequently excreted in the urine.
What is ecgonine benzoate used for?
It is the main pharmaceutical ingredient in the investigational drug Esterom, a topical solution used for the relief of muscle pain that is not FDA approved or on the market in the United States. Ecgonine benzoate is a benzoate ester metabolite of cocaine formed by hydrolysis of the methyl ester group, catalysed by carboxylesterases.
What drugs have the same metabolite As benzoylecgonine?
No other drug, prescription or illegal, produces the same metabolite as benzoylecgonine, making it a clear indication of cocaine usage. WebMD reports that 14 percent of adults in the United States have tried cocaine.
Why is my benzoylecgonine level 300 ng/mL?
The immunoassay cutoff concentration of 300 ng/mL cannot detect such a low level of benzoylecgonine. Moreover, cocaine has poor cross-reactivity with the antibody specific for benzoylecgonine (reported cross-reactivity of cocaine with the EMIT assay was 25,000 ng/mL).