What happens if the superior olivary complex is damaged?

Unilateral or bilateral lesions of the superior olivary complex (SOC) were made by local injection of kainic acid through a micropipette lowered stereotaxically into the rat’s auditory brain stem. The lesions had the effect of destroying cell bodies in the superior olive without disrupting fibers of passage.

What happens in the superior olivary complex?

The superior olivary complex (SOC) or superior olive is a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system.

Where is the superior olivary complex found?

pons
Gross anatomy. The superior olivary nuclei are located in the pons, while the inferior olivary nuclei are located in the medulla. It is generally situated caudally near the facial nucleus, in the tegmentum of the caudal pons. At the level of the pontomedullary junction, it is lateral in the reticular formation.

What is the function of the inferior Colliculi?

Almost all ascending and descending auditory pathways between the brain stem and forebrain synapse within the inferior colliculus. Principal functions of the inferior colliculus involve sound localization, frequency determination, and integration of auditory with nonauditory systems.

What does the inferior olivary nucleus do?

The inferior olivary nuclei receive movement-related information from several sources, including the spinal cord and motor cortex. This includes information about current movement, body position, muscle tension, and intention.

Where is the inferior olivary nucleus located?

superior medulla
The inferior olive nuclei are in the superior medulla, just inferior to the pons. Their composition is the grey matter in the shape of crenated “C,” in which the hilum is medially directed. The hilum faces the opposite inferior cerebellar peduncle (ICP), and a large number of fibers travel to and from it.

What do the superior and inferior colliculi form?

In mammals, the superior colliculus forms a major component of the midbrain. It is a paired structure and together with the paired inferior colliculi forms the corpora quadrigemina. The superior colliculus is a layered structure, with a pattern that is similar to all mammals.

What is the olivary nuclear complex?

Olivary nuclei The inferior olivary nucleus (or ‘complex’), which is a part of the olivo-cerebellar system and is mainly involved in cerebellar motor-learning and function. The superior olivary nucleus, considered part of the pons and part of the auditory system, aiding the perception of sound.

What is Hypertrophic olivary degeneration?

Hypertrophic olivary degeneration (HOD) is a rare neurological condition caused by degeneration in the brain stem, the structure that connects the brain to the spinal cord.[12981] Signs and symptoms include palatal tremors, lack of movement coordination (ataxia), Holmes tremor, vision problems, muscle weakness, and …

What does the inferior olivary complex do?

What is olivary nucleus?

The inferior olivary nucleus (ION), is a structure found in the medulla oblongata underneath the superior olivary nucleus. In vertebrates, the ION is known to coordinate signals from the spinal cord to the cerebellum to regulate motor coordination and learning.

What is the superior olivary complex?

(Superior olivary nucleus is labeled at center right.) The superior olivary complex ( SOC) or superior olive is a collection of brainstem nuclei that functions in multiple aspects of hearing and is an important component of the ascending and descending auditory pathways of the auditory system.

What is the difference between the medial superior and lateral superior olivary?

The medial superior olivary nucleus (MSO), which forms a distinct vertical bar within a diffuse group of periolivary nuclei, is the principal nucleus in the human superior olivary complex ( Figs. 21.8B, C and 21.10 ). The lateral superior olivary nucleus (LSO), located lateral to the MSO, is less distinct.

Is the inferior colliculus tonotopically organized?

In fact, it is observed that people can detect interaural differences down to 10 μs. The nucleus is tonotopically organized, but the azimuthal receptive field projection is “most likely a complex, nonlinear map”. The projections of the medial superior olive terminate densely in the ipsilateral central nucleus of the inferior colliculus (CNIC).

Is the superior olivary nucleus (SoC) inter species variation significant?

Overall, the SOC displays a significant interspecies variation, being largest in bats and rodents and smaller in primates. The superior olivary nucleus plays a number of roles in hearing.