What are the defects of tablet coating?
Defects in film-coated tablets
- Tablet Picking.
- Orange Peel/ Roughness.
- Tablet Edge Chipping/ Erosion.
- Bridging of Logos (Intagliations)
- Cracking of film coatings.
- Film Peeling and Flaking.
- Infilling of Logos.
- Tablet Surface Erosion.
What are the coating defects?
17 possible coating defects that may occur:
- Blistering. Description: Small to large broken or unbroken bubbles; the surface may feel like sandpaper.
- Blushing. Description: Flat finish with a milky appearance.
- Checking.
- Cracking.
- Cratering.
- Delamination.
- Fish Eyes.
- Mud Cracking.
What is the coating on tablets?
Tablet coating is the process where coating material is applied to the surface of the tablet to achieve the desired properties of dosage form over the uncoated variety. The advantages of coating are listed below. There are three main processes for tablet coating: sugar coating, film coating, and enteric coating.
Which of the following is colour defect in tablets?
MOTTLING Mottling’ is the term used to describe an unequal distribution of colour on a tablet, with light or dark spots standing out in an otherwise uniform surface. Reason: One cause of mottling may be a coloured drug, whose colour differs from the colour of excipients used for granulation of a tablet.
What causes discoloration of tablets?
Discoloration is seen either through or on the coating, caused by interactions of ingredients in the core or by heat from the process causing ingredients in the core to migrate through the coating. Problem is commonly seen with nutraceutical products.
What is blooming in tablets?
Blooming/Dull film In other words, it is the fading or dulling of a coated tablet color after a prolonged period of storage at a high temperature.
Why do tablets crack?
The cracks occur mainly due to exaggerated and rapid expansion of the tablets, this is mainly when deep concave punches are employed during the processing stages of the tablet.
Why is tablet coating done?
Appearance: to change the color for branding purposes or other aesthetic reasons. Stability: to protect the active ingredient from moisture, light, and/or acidic environment of the stomach. Taste and/or odor masking: to provide an easy to swallow tablet without the bitter taste of many active ingredients.
What are the types of coated tablet?
Types and Functionality of Tablet Coating
- Sugar Coated Tablets.
- Film Coated Tablets.
- Gelatin Coated Tablets.
- Enteric Coated Tablets.
- Compression Coating Tablets.
- Other Types.
What is tablet shellac coating?
Shellac is a natural polymer, which is used as enteric coating material in pharmaceutical applications. The major objective of the present study was to investigate the potential of shellac for other purposes, namely to provide moisture-protective and taste-masking coatings as well as extended-release matrix tablets.
What is lamination in tablet?
Lamination of tablets happens when the product separates into horizontal layers. Lamination is very similar to capping, but occurs in the main body of the tablet, not at the top, and it can occur immediately after compression or during the storage period.
Why do tablets turn yellow?
If your home is unusually hot during spring and summer, your medications could lose their potency. Look for these changes if you suspect medications have been compromised by heat: 1. Different color: If tablets are white, for example, they may turn yellow.
What are the defects of film coating in tablets?
7. CRATERING • It is defect of film coating whereby volcanic-like craters appears exposing the tablet surface • Reason: The coating solution penetrates the surface of the tablet, often at the crown where the surface is more porous, causing localized disintegration of the core and disruption of the coating.
How are the uncoated tablets coated?
The uncoated tablets have been coated by using the specific aqueous film coating formulation under the specified coating variables during the coating process to observe the affect of the formulation on the tablet properties.
What is tablet pitting defect?
It is a coating defect where pits appear on the surface of a tablet core without any visible disruption of the film coating. In other words, pitting is the deformation of the core of the tablet without any visible signs of disruption of the film coating. 1. Inappropriate drying (inlet air) temperature.
What is a capping defect in a tablet?
Capping Capping is a defect in which the top of the tablet— the area above the band—cleaves (photo). It can be a stealthy defect, undetected until hardnesss and friability testing or until entering the pre-heat cycle of the coating process.