Is Lamictal water soluble?

Lamotrigine is very slightly soluble in water (0.17 mg/mL at 25°C) and slightly soluble in 0.1 M HCl (4.1 mg/mL at 25°C), having plasma half-life of 24 to 35 hours [10].

Is 200 mg lamotrigine a lot?

However, the dose is usually not more than 200 mg a day. Adults taking valproic acid (Depakote®)—At first, 25 mg of lamotrigine once every other day for 2 weeks, then 25 mg once a day for 2 weeks. After this, your doctor may gradually increase your dose as needed.

What are the side effects of Lamictal 200 mg?

Common side effects may include:

  • headache, dizziness;
  • blurred vision, double vision;
  • tremor, loss of coordination;
  • dry mouth, nausea, vomiting, stomach pain, diarrhea;
  • fever, sore throat, runny nose;
  • drowsiness, tired feeling;
  • back pain; or.
  • sleep problems (insomnia).

What are the symptoms of Lamictal toxicity?

Toxic symptoms are symptoms experienced when the blood Lamictal level is too high. Toxic symptoms can include drowsiness, incoordination, slurred speech, dizziness, headache and coma.

What can you not mix with lamotrigine?

The following medications may decrease the level and effect of lamotrigine: Anticonvulsants such as phenytoin (Dilantin®), carbamazepine (Tegretol®/Carbatrol®/Equetro®), phenobarbital, and primidone (Mysoline®) Oral contraceptives (birth control pills) Rifampin (Rifadin®), ritonavir (Norvir®)

How quickly is lamotrigine absorbed?

It is rapidly absorbed, reaching peak concentrations within about 3 hours postdose. The bioavailability of the oral formulation is about 98%. The area under the plasma concentration-time curve indicates dose-linear pharmacokinetics. The degree of plasma protein binding is 56%.

Does Lamictal give you energy?

How does Lamictal make you feel? Like all drugs, Lamictal affects each person differently when they take it. For example, Lamictal typically doesn’t give you energy. In fact, you may have fatigue (lack of energy) as a side effect.

How many mg of Lamictal is lethal?

Conclusions: Most cases reporting lamotrigine exposures observed mild or no toxicity; however, large exposures were associated with severe CNS depression, seizures, cardiac conduction delays, wide complex tachycardia, and death. In adults with a serum concentration >25 mg/L, severe toxicity may occur.

Can I take vitamin D with lamotrigine?

Interactions between your drugs No interactions were found between lamotrigine and Vitamin D3.

What vitamins should not be taken with Lamictal?

Interactions with Lamotrigine

  • Ginkgo Biloba.
  • Kava Kava.
  • Vitamin B9 (Folic Acid)
  • Vitamin D.
  • Vitamin H (Biotin)

What is the color of the Lamictal 200mg bottle?

Lamictal 200 mg hexagonal, blue, imprinted with LAMICTAL 200 Lamictal 25 mg shield, white, imprinted with LAMICTAL 25 Lamotrigine 100 mg 009047008

What are the different strengths of Lamictal?

They’re available in these strengths: 2 mg, 5 mg, and 25 mg. * A suspension is a liquid with particles in it. The following table details Lamictal dosages for bipolar I disorder in adults.

Is Lamictal soluble in water?

Lamotrigine is very slightly soluble in water (0.17 mg/mL at 25°C) and slightly soluble in 0.1 M HCl (4.1 mg/mL at 25°C). The structural formula is: LAMICTAL tablets are supplied for oral administration as 25-mg (white), 100-mg (peach), 150-mg (cream), and 200-mg (blue) tablets.

What is GlaxoSmithKline Lamictal?

It is supplied by GlaxoSmithKline. Lamictal is used in the treatment of bipolar disorder; schizoaffective disorder; epilepsy; seizure prevention and belongs to the drug class triazine anticonvulsants. Risk cannot be ruled out during pregnancy. Lamictal 200 mg is not a controlled substance under the Controlled Substances Act (CSA).