How do you administer amiodarone infusion?

The current dosing recommendation for intravenous amiodarone is to give ≈1000 mg over the first 24 hours. The initial infusion should contain 3 mL of amiodarone injection (150 mg) in 100 mL D5W (concentration of 1.5 mg/mL). One should infuse this 100 mL over 10 minutes (15 mg/min) for a total of 150 mg.

How long do you infuse amiodarone?

Amiodarone may be used prior to direct current (DC) cardioversion. Loading dose: The standard recommended dose is 5mg/kg bodyweight given by intravenous infusion over a period of 20 minutes to 2 hours. This should be administered as a dilute solution in 250 ml 5% dextrose.

How do you prepare amiodarone IV?

To prepare Amiodarone for an IV infusion, mix with D5W and give through an in-line filter. Alternatively, it is NOT necessary to dilute amiodarone for IV push administration and a filter is not necessary. When infusions exceed 2 hours, amiodarone can absorb into the plastic used for standard IV bags.

What should you check before administering amiodarone?

Your doctor will order certain tests, such as blood tests, X-rays, and electrocardiograms (EKGs, tests that record the electrical activity of the heart) before and during your treatment to be sure that it is safe for you to take amiodarone and to check your body’s response to the medication.

Can amiodarone be given via peripheral line?

Intravenous administration IV amiodarone must be administered via a central line. The only exception is the treatment of cardiac arrest; in this situation amiodarone may be administerd peripherally with extreme care to avoid extravasation.

When should I start IV after amiodarone?

Pa- tients who have been receiving IV therapy for more than 2 to 3 weeks can be started safely on mainte- nance doses of oral amiodarone (300- 400 mg/d).

When should you not give amiodarone?

Amiodarone therapy is contraindicated in patients with second- or third-degree heart block who do not have a pacemaker. Intravenously administered amiodarone causes heart block or bradycardia in 4.9 percent of patients and hypotension in 16 percent.

When do you hold amiodarone in nursing?

Hold the medication if HR < 60/min or > 120/min. Assess other vital signs like blood pressure and respirations.