Can drugs cause seizures in babies?

We identified 142 pediatric drug-induced seizure cases (56% male), which represent nearly 5% of pediatric cases requiring bedside consultation by medical toxicologists. One-hundred and seven cases (75%) occurred in children aged 13-18 years, and 86 (61%) resulted from intentional ingestions.

What can trigger a seizure in an infant?

What to know about seizures in babies. Baby seizures happen when an abnormal extra burst of electrical activity occurs between neurons, or brain cells, in a baby’s brain. These can happen for many reasons. Causes may include brain injury, infection, and underlying health conditions, such as cerebral palsy.

What is a drug-induced seizure?

Drug-induced seizures are adverse reactions caused by several drugs, and there are no clinical features to differentiate them from idiopathic epileptic seizures. The term includes seizures associated with antiepileptic drugs.

Which of the following is the most common cause of seizures in infants?

A The most common cause of seizures in newborn infants is brain damage from illness or injury, such as hypoxic-ischemic encephalopathy (HIE) (5).

What recreational drugs can cause seizures?

Amphetamines, ecstasy, cocaine and heroin have all been shown to increase the frequency of seizures in people with epilepsy. The use of cannabis is also best avoided. For some people, using recreational drugs can trigger epilepsy. They can also be a risk factor for SUDEP (Sudden Unexpected Death in Epilepsy).

Can certain drugs cause seizures?

Drugs That Can Cause Seizures Amphetamines. Methamphetamine. MDMA. Opioids.

What are signs of seizures in babies?

What are the symptoms of a seizure in a child?

  • Staring.
  • Jerking movements of the arms and legs.
  • Stiffening of the body.
  • Loss of consciousness.
  • Breathing problems or stopping breathing.
  • Loss of bowel or bladder control.
  • Falling suddenly for no apparent reason, especially when associated with loss of consciousness.

What does it look like when an infant has a seizure?

Subtle seizures are more common among full-term babies. Symptoms of subtle seizures include: Random or roving eye movements, eyelid blinking or fluttering, eyes rolling up, eye opening, staring. Sucking, smacking, chewing and protruding tongue.

How common are drug-induced seizures?

Seizures are a common toxic complication of numerous drugs and poisons, as well as drug withdrawal syndromes. Studies have estimated that 6% of new‐onset seizures and up to 9% of status epilepticus cases are due to drug toxicity 1, 2.

Can drug-induced seizures cause brain damage?

Seizures are a serious complication associated with medication or drug use, which can result in hyperthermia, acidosis, anoxic brain injury, an eightfold risk of aspiration pneumonitis, and nearly 2% mortality [3, 4].

How do you treat seizures in infants?

What to Do if Your Child Has a Seizure:

  1. Gently place your child on the floor or ground, and remove any nearby objects.
  2. Lay your child on his or her side to prevent choking on saliva (spit).
  3. If your child vomits, clear out the mouth gently with your finger.
  4. Loosen any clothing around the head or neck.

What do seizures look like in infants?

More pronounced signs may include the baby’s arms coming up with a slight head nod and their eyes rolling up. While this type of movement may look like the baby is just startled, spasms may occur for five to ten seconds in a cluster for several minutes when the baby first wakes up or is going to sleep.

What is the pathophysiology of drug‐induced seizures?

Drug‐induced seizures can occur as a direct result of altering neural pathways and specific excitatory or inhibitory transmitters and receptors within those pathways. Figure 1offers a simplified representation of these processes.

Which drugs cause drug-induced seizures?

Patients exposed to a stimulant were found to be at a statistically significant increased risk of death. 8 Further, it had emerged that poison control centers were being consulted regarding three agents commonly causing drug-induced seizures: bupropion, tramadol, and venlafaxine. 8

What is the first‐line treatment for drug‐induced seizures?

Benzodiazepines are the first‐line treatment for drug‐induced seizures, with addition of pyridoxine if isoniazid or other hydrazine toxicity is suspected. If benzodiazepines fail to terminate seizures, second‐line agents include barbiturates and propofol.

What are the drug-induced seizures and how are they treated?

• Use of drugs known to cause seizures should be avoided in patients with predisposition to seizures. • Most drug-induced seizures resolve after discontinuation of the offending drugs, but some patients require supplementary treatment, eg, intravenous diazepam.