Which has less side effects tamoxifen or Arimidex?

The latest ATAC analysis also found that the overall risk of side effects (both serious and not-so-serious) was lower for Arimidex compared to tamoxifen. Earlier ATAC results showed that serious side effects were less common in women taking Arimidex compared to women taking tamoxifen.

Which one is better tamoxifen or anastrozole?

Previously reported results showed that anastrozole was slightly better than tamoxifen in preventing recurrence. The 10-year breast cancer–free interval rate was 89.2% for tamoxifen and 93.5% for anastrozole (P = . 03).

Is tamoxifen safer than anastrozole?

Ten-year breast cancer—free survival was estimated to be 93.5% with anastrozole versus 89.2% with tamoxifen; however, a subgroup analysis showed that anastrozole was not superior to tamoxifen in women older than 60 years.

Is Arimidex more effective than tamoxifen?

At the virtual San Antonio Breast Cancer Symposium, researchers presented 12-year results for tamoxifen versus anastrozole [Arimidex], which demonstrated no significant difference in terms of disease recurrence in postmenopausal women with hormone-receptor-positive ductal carcinoma in situ, or DCIS; but the two …

Is there a better drug than tamoxifen?

Dec. 11, 2002 (San Antonio, Texas) — Results of a long-term study show the relatively new drug Arimidex appears to work better than the standard medicine tamoxifen in fighting early breast cancer in postmenopausal women.

Should I switch from tamoxifen to anastrozole?

Conclusions: Switching to anastrozole after the first 2-3 years of treatment was confirmed to improve event-free and relapse-free survival of postmenopausal, node-positive, ER-positive early breast cancer patients already receiving adjuvant tamoxifen.

What are the long-term side effects of Arimidex?

Examples of the long-term side effects of Arimidex include:

  • osteoporosis (bone weakness) or bone fractures.
  • depression.
  • increased cholesterol levels.
  • liver problems.
  • hair loss or hair thinning.

What can I replace tamoxifen with?

Based on results of a major new study, anastrozole (Arimidex) should replace tamoxifen as the drug of choice for preventing recurrent breast cancer in postmenopausal women with early, localized hormone-receptor-positive breast cancer.

What is an alternative drug to tamoxifen?

What’s more, one of the aromatase inhibitors, a drug called Femara, or letrozole, has been shown to take over after five years of tamoxifen and keep the benefit going. The other two may do the same. Some doctors would now start with Arimidex or the others instead of tamoxifen.

Is aromatase inhibitor better than tamoxifen?

For women with early-stage oestrogen receptor (ER)-positive breast cancer, adjuvant tamoxifen reduces 15-year breast cancer mortality by a third. Aromatase inhibitors are more effective than tamoxifen in postmenopausal women but are ineffective in premenopausal women when used without ovarian suppression.

Is there a substitute for Arimidex?

The main alternative to arimidex is [Aromasin] (http://en.wikipedia.org/wiki/Exemestane)

What are the Common side effects of tamoxifen?

Side effects of tamoxifen may include: Menopause-like symptoms, including hot flashes, night sweats and vaginal dryness. Weight gain (more common) or fluid retention . Irregular or loss of menstrual periods. Leg swelling. Nausea. Vaginal discharge. Skin rash. Erectile dysfunction. Fatigue. Headaches. What are the risks of taking tamoxifen? Rarely, tamoxifen may cause serious problems such as:

Should aromatase inhibitors replace tamoxifen?

Most women take hormonal therapy for 5 to 10 years after breast cancer surgery. Both tamoxifen and aromatase inhibitors can cause side effects. Tamoxifen may cause hot flashes and increase the risk of blood clots and stroke. Aromatase inhibitors may cause muscle and joint aches and pains.

How much does Arimidex increase survival?

High cholesterol levels. Arimidex may increase your cholesterol levels.

  • Allergic reaction.
  • Osteoporosis (weakened bones).
  • Ischemic heart disease (a heart condition that affects blood flow to your heart).
  • Liver problems.
  • Females who have not gone through menopause.