What does it mean when your ALT is high?

When liver cells are damaged, they release ALT into the bloodstream. An ALT test measures the amount of ALT in the blood. High levels of ALT in the blood can indicate a liver problem, even before you have signs of liver disease, such as jaundice, a condition that causes your skin and eyes to turn yellow.

What can cause ALT liver enzymes to be elevated?

The most common causes of elevated transaminase levels are nonalcoholic fatty liver disease and alcoholic liver disease. Uncommon causes include drug-induced liver injury, hepatitis B and C, and hereditary hemochromatosis. Rare causes include alpha1-antitrypsin deficiency, autoimmune hepatitis, and Wilson disease.

How long does it take for ALT levels to return to normal?


Marker Time to return to normal limits
Aspartate aminotransferase 7 days, but considerable variability in declines with abstinence
Alanine aminotransferase Unknown
Macrocytic volume Unknown but half–life ∼ 40 days
Carbohydrate–deficient transferrin 2–4 weeks of abstinence

What are symptoms of elevated ALT?

– Abdominal pain – Dark-colored urine – Exhaustion (feeling tired) – Itching – Jaundice (yellowing of your skin or eyes) – Light-colored stools – Loss of appetite – Nausea and vomiting

What causes high ALT?

High ALT or liver damage can be caused by various reasons, some of these common causes include: hepatitis B/C, fatty liver, NASH, alcoholic liver disease, medications, and heavy metals. The usual treatment for high ALT is to first determine the cause, and then remove it, e.g. to use anti-viral medications, go on a weight loss diet or stop drinking, etc.

What are considered dangerous levels of ALT AST liver enzymes?

The AST is typically in the 100 to 200 IU/L range, even in severe disease, and the ALT level may be normal, even in severe cases. The AST level is higher than the ALT level, and the ratio is greater than 2:1 in 70% of patients. A ratio greater than 3 is strongly indicative of alcoholic hepatitis. Full answer is here.

What causes elevated ALT and SGPT levels?

These enzymes are normally present within liver cells and to a lesser extent in the muscle cells. If the liver is injured or damaged, the liver cells spill these enzymes into the blood, which causes the SGOT and SGPT enzyme blood levels to rise. What are the normal levels of SGOT and SGPT? • Normal levels of SGOT: 5-40 unit s/liter of serum.