Can you live a normal life with polymicrogyria?
Dr. Tran explained the spectrum of care for polymicrogyria. Some patients are nonverbal, some go to school, and some even live with this condition and never know.
What are treatments for polymicrogyria?
The Polymicrogyria (PMG) malformation cannot be reversed, but the symptoms may be treated in children and adults. The first-line treatment for persons with seizures is anti-seizure medications, and the medication chosen depends on the type of seizures or epilepsy syndrome.
Is polymicrogyria a disability?
This condition causes severe intellectual disability, problems with movement, and seizures that are difficult or impossible to control with medication. Polymicrogyria most often occurs as an isolated feature, although it can occur with other brain abnormalities.
Is polymicrogyria a rare disease?
Bilateral perisylvian polymicrogyria (BPP) is a rare neurological disorder that affects the cerebral cortex (the outer surface of the brain). BPP is a subtype of a broader condition known as polymicrogyria. The cerebral cortex of the brain normally consists of several deep folds and grooves.
Is polymicrogyria genetic?
Polymicrogyria can result from both genetic and environmental causes. It may occur as an isolated finding or as part of a syndrome . Treatment is based on the signs and symptoms present in each person.
What is frontal polymicrogyria?
Bilateral frontal polymicrogyria is one of the rarest subtypes of polymicrogyria. It is a symmetric and bilateral form (in both brain hemispheres) that only involves the frontal lobes without including the area located behind the Sylvius fissure or the area located behind the Rolando sulcus.
Is polymicrogyria cerebral palsy?
Common problems associated with PMG in general are: swallowing and speech difficulties, reflux, seizures of varying degrees (about 90% are affect with seizures at some point in their lives), development delays, lack of muscle coordination, impaired cognition of varying degrees and cerebral palsy, but there can me many …
What is unilateral polymicrogyria?
Unilateral polymicrogyria is a cerebral cortical malformation characterized by unilateral excessive cortical folding and abnormal cortical layering. It comprises two sub-types depending on the areas affected: unilateral hemispheric and focal polymicrogyria (see these terms).
What is the life expectancy of polymicrogyria?
The quality of life and life expectancy for people with BPP are not well-described but may depend on severity of symptoms, whether complications develop, and whether other birth defects or an underlying syndrome are present.
What is focal polymicrogyria?
Unilateral focal polymicrogyria (BFPP) is the mildest sub-type of polymicrogyria (PMG; see this term), a cerebral cortical malformation characterized by excessive cortical folding and abnormal cortical layering, that affects only one small region of the brain and that may show no neurologic involvement.
How do you get rid of polymicrogyria?
Polymicrogyria. The symptoms experienced differ depending on what part of the brain is affected. There is no specific treatment to get rid of this condition, but there are medications that can control the symptoms such as seizures, delayed development or weakened muscles as some of the noted effects.
Is there a role for surgical management of cerebellar metastases?
Surgical management of metastases accounts for an important and increasing part of the neurosurgical workload. Treatment of patients with cerebellar metastases may deserve to be studied separately [ 9, 10, 11, 12, 25 ].
What is the prognosis of cerebellar masses?
Cerebellar masses are a heterogenous group of conditions that can cause compression of the aqueduct or fourth ventricle, resulting in obstructive hydrocephalus, brainstem compression, and upward/downward herniation as a direct result of mass effect. Untreated lesions can be fatal in a few hours, but … Treatment of cerebellar masses
Can polymicrogyria malformation be reversed?
The Polymicrogyria (PMG) malformation cannot be reversed, but the symptoms can be treated. The removal of affected areas through hemispherectomy has been used in some cases to reduce the amount a seizure activity. Few patients are candidates for surgery.