How do I return my alteplase?
If you would like a credit for your return, please contact Genentech Customer Service at (800) 551-2231 to obtain authorization and return box label. Shipping and transportation charges are prepaid by the Customer.
Who manufactures tenecteplase?
Genentech: TNKase® (tenecteplase) – Information for Patients.
How do you give Cathflo?
INJECT the 2.2 mL of Sterile Water for Injection, USP, into the Cathflo vial, directing the diluent stream into the powder. Slight foaming is not unusual; let the vial stand undisturbed to allow large bubbles to dissipate. 3. Mix by gently SWIRLING until the contents are completely dissolved.
Can you reconstitute alteplase with normal saline?
Conclusions: Alteplase diluted in normal saline solution at a concentration of 0.01 mg/mL is biochemically stable and active at ambient temperature for as long as 24 hours as assessed by in vitro clot lysis assays.
How much does TNKase cost?
The cost for TNKase intravenous powder for injection 50 mg is around $7,305 for a supply of 1 powder for injection, depending on the pharmacy you visit. Prices are for cash paying customers only and are not valid with insurance plans.
What is Cathflo used for?
Cathflo® Activase® (Alteplase) is indicated in adult and pediatric patients for the restoration of function to central venous access devices that have become occluded due to a blood clot.
Can Cathflo cause bleeding?
Common side effects of Cathflo Activase include: bleeding (may be serious), blood clots, and. infection.
What do you dilute tPA with?
Results in concentration of 1 mg/ml. May be infused at this concentration or may dilute further with equal volume of normal saline or D5W (0.5 mg/ml).
How do you mix Activase?
Reconstitution should be carried out using the transfer device provided and by adding the contents of the 100‑mL vial of preservative free SWFI to the 100-mg vial of Activase powder. Reconstitute Activase immediately before administration, using aseptic technique at all times.
How much does tPA cost?
The direct cost of IV tPA in the United States approximates $7000/100-mg vial. This reflects only the actual price of the drug and not the additional ancillary expenses of delivering it. This expense represents an area of potential savings for patients treated with combination therapy.
How do you give streptokinase to MI?
The adult dose of streptokinase for AMI is 1.5 million U in 50 mL of 5% dextrose in water (D5W) given IV over 60 minutes. Allergic reactions force the termination of many infusions before a therapeutic dose can be administered.
What is the return policy for TNKase products?
The procedure for returning products depends on the condition of the product. Unless requested, all TNKase expired returns will be replaced. If you would like a credit for your return, please contact Genentech Customer Service at (800) 551-2231 to obtain authorization and return box label.
What are the side effects of TNKase?
Nausea and/or vomiting, hypotension, and fever have also been reported. Return to Table of Contents DOSAGE AND ADMINISTRATION Dosage TNKase is for intravenous administration only. The recommended total dose should not exceed 50 mg and is based upon patient weight. A single bolus dose should be administered over 5 seconds based on patient weight.
What is the final concentration of TNKase?
Final concentration of TNKase is 5 mg/mL. Determine the correct dose of TNKase based on patient weight. TNKase is for IV administration only. WITHDRAW the appropriate volume of solution based on patient weight. The recommended total dose should not exceed 50 mg. Discard solution remaining in the vial.
Is TNKase a thrombolytic?
TNKase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a “clot-busting” drug. It helps your body produce a substance that dissolves unwanted blood clots. TNKase is used to prevent death in people who have had a heart attack (acute myocardial infarction).